Native vs. Web vs. Hybrid - Building the App You Need: Native apps are developed to run on a particular OS or a mobile device. While web apps are built on HTML5 and are designed to run in a browser, now let’s see what hybrid apps are all about. The hybrid app is a combination of both native and web apps. They are unique and different. To harness the capabilities of both native and web app, a hybrid app is the best option. Many enterprises are opting for a hybrid app.